Preventing bed bugs is far easier than getting rid of them, so this area should always be a priority. When traveling, inspect beds and furniture in hotels for signs of bed bugs. Vacuum out suitcases after returning home. Use caution when purchasing items that are used, as bed bugs can come into the home on everything from blankets to clothing. Bites on the skin can also be a sign. If you do spot any signs of bed bug infestation, address it immediately, as they can reproduce quickly.